GeneProf says..

"Hi! Welcome to GeneProf!"

GeneProf is a web-based, graphical software suite that allows users to analyse data produced using high-throughput sequencing platforms (RNA-seq and ChIP-seq; "Next-Generation Sequencing" or NGS): Next-gen analysis for next-gen data!

Some of GeneProf's highlights include:

  • Easy-to-use web-based interface:Access your data at any time from any reasonably modern computer with a working internet connection -- no need to install any software! (cp. Section 'System Requirements').
  • Analysis wizards make your life easy:Pre-defined, step-by-step workflows make it possible for anybody to analyse their short read data in a minimum of hands-on time. (cp. SubConcept 'Analysis Wizards').
  • Versatile modules:Advanced users and data analysis experts benefit from GeneProf's broad range of analysis modules, which can be combined freely a minimum of hands-on time (cp. Concept 'Workflows').
  • Integrated Analysis:Analysis of ChIP-seq and RNA-seq data in one place, plus support for the integration of other external data (e.g. from microarrays).
  • Comprehensive Resource:GeneProf provides a comprehensive resource of analyzed next-generation sequencing data. Experimental results can be easily accessed and compared and the analysis procedures employed to produce the data are fully transparent and can be accessed readily (cp. Tutorial 'Examining Public Next-Gen Data..').
  • Extensibility:Algorithm developers and computer programmers can develop their own modules and extend the functionality of GeneProf. Existing software can be easily wrapped and integrated in the GeneProf framework (cp. Section 'Module Development: Adding new..') and data from GeneProf may be used externally (cp. Section 'Web API: Retrieving Data from ..').

GeneProf is academic software developed at the Centre for Regenerative Medicine / Institute for Stem Cell Research, University of Edinburgh and has benefited from funding by the Medical Research Council and the EU Framework 7 Project "EuroSyStem".

If you use GeneProf for your work, please provide accession numbers for your data analysis experiment(s) and cite:

, , . GeneProf: analysis of high-throughput sequencing experiments. Nature Methods 9(1), 7-8 (). PubMed ID: 22205509, Full Article @ Nature Methods.

Further information about GeneProf, the authors and how to cite in the Introduction section. Also check out our screencasts section for a collection of videos about GeneProf!

Things you might want to do..

Search GeneProf

Interested in the expression and regulation of a particular gene? Looking for experiments related to your research or would you like to look up a particular record by accession ID? Just enter your search term below!

Browse Public Data

GeneProf hosts a wealth of analysed next-gen sequencing data. You might be able to find something interesting -- there are currently 140 public experiments for you to explore!

Analyse your own Next-Gen Data

You can start analysing it right now! Just start a new experiment, upload your data and use one of our straightforward analysis wizards to get started.

Sorry, you will have to log in before you can use this feature!

Learn how to make better use of GeneProf

New to GeneProf? You might like to look through the tutorials section of the manual! Popular tutorials include:

GeneProf Web Services

GeneProf provides programmatic access to much of the data stored in its databases via a collection of RESTful web services. The services are well documented and there are many examples, so why not give it a go?

Screencasts

Watch one of our short screencasts introducing GeneProf and how to use it!

More features are available for registered users. Don't worry, registration is free and only takes a few minutes! Why not register right now..?

Already got a user account?

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Latest News:
30-Jan-2013

New Workflow Designer

GeneProf now features an improved, faster and prettier workflow designer tool! Read more..
23-Jan-2013

Paired-end FASTQ

The new version of GeneProf (launched today) brings better support for paired-end FASTQ files via the data analysis wizards! Read more..
17-Dec-2012

Genome Browser fixed

An issue that resulted in the genome browser not being updated after changing the track selection has been fixed. Read more..
Older Messages? Open News Archive.
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GeneProf as a Resource:
GeneProf's databases host a wealth of public, ready-analysed and attainable data from a variety of RNA-seq, ChIP-seq and other high-throughput sequencing experiments.
Latest Public Experiments:
Here's a list of some of the latest additions to GeneProf's public data repository:
ENCODE2013 Data: Histone Modifications by ChIP-seq from ENCODE/Broad Institute analysed by
Besnard2012 Data: Unraveling cell type-specific and reprogrammable human replication origin signatures associated with G-quadr.. analysed by
RadaIglesias2011 Data: A unique chromatin signature uncovers early developmental enhancers in humans analysed by
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Random Genome Snapshot:
Use GeneProf to explore genomic data in depth using the built-in genome browser functionality. There are lots of tracks available for you to look through -- check out the example below or click here for a one-page overview of all public genome browser tracks!
Oct4 locus
(from gpXP_000127)